- Several drugs are used in combination in multidrug therapy (MDT).These drugs must never be used alone as monotherapy for leprosy.
- A single dose of combination therapy has been used to cure single lesion paucibacillary leprosy: rifampicin (600 mg), ofloxacin (400 mg), and minocycline (100 mg). The child with a single lesion takes half the adult dose of the 3 medications.
- Any patient with a positive skin smear must be treated with the MDT regimen for multibacillary leprosy.
